Depression is becoming a major problem for millions of people all around the world and the prescribed therapy may be helpful but with many adverse effects. Hence, when an alternative method pops up people are more willing to go for it and try to solve their issue. According to a conducted study that has been released in journal Psychopharmacology the solution for treating depression could be the psychedelic toad milk.
Toad – The Alternative Treatment of Depression
It is known for its poisonous secretions that have the ability to kill predators and make humans high. The toad in US can reach up to 7 inches in length having the ability to obtain water by osmotic absorption through its abdomen. Moreover, it excretes a whitish substance that is high in 5-MeO-DMT, a compound that represents a variation of DMT also presenting the mild-altering psychedelic brew ayahuasca.
When the toad milk gets dried and smoked, according to researchers it creates a short but potent psychedelic experience reflecting mystical insights. It is so strong that a single inhalation of vapor has in its content 5-methoxy-N, N-dimethyltryptamine (5-MeO-DMT) that boosts the feeling of satisfaction in life, releases the mind and reduces psychopathological symptoms.
It has been proven that the dried secretion of the Colorado River toad, or Bufo alvarius, can be a potent and fast alternative for managing depression.
As a result of this many alternative therapists turn to the use of toad gunge in the treatment of psychological and emotional disorders.
Researches on Toad
Experts have performed a series of psychiatric tests in order to determine the effect of smoking the dried secretion. In this study were involved 42 participants who smoked this secretion and reported a decrease in depression and anxiety. Percentage wise, the average depression ratings were down by 18%, the anxiety by 39% and stress by 27%, just in one day of use of this substance.
After a month of its use, the rates got reduced dramatically, namely the depression ratings got reduced to 68% below baseline levels, anxiety to 56% and stress to 48%.
Researchers believe that these positive results come as a result of the elevation in neurogenesis, or due to the relief in neuropsychiatric diseases by binding to sigma-1 receptors in the brain thus regulating the inflammation.
However, although there has been positive results the researchers are still not willing to share them with the rest of the world as the toad might be exploited through excessive milking or black market trading.
In addition to this, toads are already being protected in the states like California, Arizona, and New Mexico, prohibiting their taking out of their native state. On the other hand, California has declared them “endangered”, and New Mexico lists them as “threatened.”
Yet, there is still hope for the people who suffer from depression as synthetic 5-MeO-DMT can be easily synthesized in a lab, and its positive effects have been confirmed by a conducted study. The performed study at the John Hopkins University demonstrated that that the use of the synthetic version can reduce depression and anxiety in 80% of the people.